October 5, 2008

INTERSTITIAL PDT FOR PRIMARY AND METASTATIC TUMOUR



Photo courtesy of House of Laser


PDT is one of the interesting modalities in cancer treatment.The availability of several photosensitizers and lasers are opening new pathways in photodynamic medicine, leading to a new era in the future of medicine.
(It should be mentioned that PDT will not be an umbrella only in oncology but will cover some areas including infectious and other degenerative processes or diseases as well.)
A technique of interstitial PDT has been offered in conjunction with other modalities in cancer treatment,as shown in this picture.
Selective cancer cells death by apoptosis and necrosis has been proposed to a formation of lysate following cytotoxic process of cancer cells.
Secondly vascular shutdown is another way to the killing of cancer cells.
Positive immune response is another way leading to improvement of patient condition.(see: Immunologic aspect of PDT/Laser therapy,a review by Santoso Cornain,MD,D.Sc, a link in this blog)